abstract：OBJECTIVE:The purpose of this study is to compare the thyroid hormone (TH) profile in male infertile subjects with normal and altered sperm parameters and assess its relationship with spermogram and reproductive hormones. DESIGN:This cross-sectional study was conducted in Karachi from August 2017 till September 2018 o...

journal_title：International journal of clinical practice

authors： Rehman R,Zafar A,Fatima SS,Mohib A,Sheikh A

更新日期：2020-09-01 00:00:00

abstract：AIM:Variations of dopamine receptor type 2 (DRD2) are among the key factors involved in the pathology of schizophrenia. Presence of certain SNPs in DRD2 gene also amend patients' response to antipsychotics. Keeping in view the genetic diversity among populations and important role of DRD2 polymorphisms in schizophrenia...

journal_title：International journal of clinical practice

authors： Amir QU,Hanif F,Washdev W,Bilwani F,Usman Simjee S

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:The available evidence regarding the possible effects of resveratrol on liver function is inconsistent. Therefore, the present meta-analysis was performed to investigate the overall effects of resveratrol supplementation on liver enzymes in adults. METHODS:A systematic and comprehensive search of the online...

journal_title：International journal of clinical practice

authors： Darand M,Farrokhzad A,Ghavami A,Hadi A,Karimi E,Fadel A,Askari G

更新日期：2020-08-31 00:00:00

abstract：BACKGROUND:We aimed to investigate the effect of a low-protein intake on all-cause mortality in subjects with an estimated glomerular filtration rate (eGFR) ≧60 mL/min/1.73 m2 with or without albuminuria using data from the National Health and Nutrition Examination Survey (NHANES). METHODS:We analysed participants in ...

journal_title：International journal of clinical practice

authors： Lee CL,Liu WJ,Wang JS

更新日期：2020-07-01 00:00:00

abstract：AIMS:Strong evidence indicates that drugs reduce blood lipids and improve cardiovascular end-points, leading to their wide usage. However, the success of these drugs can be affected by poor patient's adherence to prescribed medication. This study aimed to evaluate medication adherence in patients with dyslipidaemia in ...

journal_title：International journal of clinical practice

authors： Shakarneh JK,Hallak HO,Awadallah HB,Al-Hamed DH,Khdour MR

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Ageing is intrinsically associated with a progressive decline in cardiorespiratory fitness (CRF) as measured by peak oxygen uptake (VO2peak ). Improving CRF through physical activity contribute to better and healthy ageing. High-intensity interval training (HIIT) is a potent method of improving CRF among sen...

journal_title：International journal of clinical practice

authors： Bouaziz W,Malgoyre A,Schmitt E,Lang PO,Vogel T,Kanagaratnam L

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Alternatives to acute hospital admission are required to accommodate the increasing pressures on health services. Since physiotherapists and occupational therapists are integral to inpatient teams, they may also be integral to admission replacement services, and thus their roles in these services merit inves...

journal_title：International journal of clinical practice

authors： Harris C,Ignatowicz A,Lasserson DS

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Anticoagulant therapy in patients with atrial fibrillation (AF) increases the risk of minor bleeding, which is mostly accepted by patients. We aimed to assess whether continuation of anticoagulation despite minor bleeding is associated with a higher level of knowledge on AF and anticoagulation. METHODS AND ...

journal_title：International journal of clinical practice

authors： Metzgier-Gumiela A,Skonieczny G,Konieczyńska M,Desteghe L,Heidbuchel H,Undas A

更新日期：2020-06-01 00:00:00

abstract：OBJECTIVE:While physical activity (PA) is known to have positive effects on psychological and physical health, little is understood about the association between non-compensatory PA (ie, not compulsive or intended to control weight or shape) and psychopathology among individuals with eating-disorder features. The prese...

journal_title：International journal of clinical practice

authors： Kerrigan SG,Lydecker JA,Grilo CM

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Platelet-rich plasma (PRP) is a blood component therapy with a supraphysiological concentration of platelets derived from allogenic or, more commonly, autologous blood. PRP has been used in different non-transfusion indications because of its role in the promotion of tissue repair and healing, in fields su...

journal_title：International journal of clinical practice

authors： Pachito DV,Latorraca COC,Riera R

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:Cariprazine is an oral antipsychotic approved in the US for the treatment of schizophrenia, acute bipolar mania, and most recently, bipolar depression. The aim of this systematic review is to describe the efficacy, tolerability and safety of cariprazine for the treatment of depressive episodes associated with...

journal_title：International journal of clinical practice

authors： Citrome L

更新日期：2019-10-01 00:00:00

abstract：AIMS:To analyse the predictive capacity of 15 machine learning methods for estimating cardiovascular risk in a cohort and to compare them with other risk scales. METHODS:We calculated cardiovascular risk by means of 15 machine-learning methods and using the SCORE and REGICOR scales and in 38 527 patients in the Spanis...

journal_title：International journal of clinical practice

authors： Quesada JA,Lopez-Pineda A,Gil-Guillén VF,Durazo-Arvizu R,Orozco-Beltrán D,López-Domenech A,Carratalá-Munuera C

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Urinary tract infections (UTI) and asymptomatic bacteriuria (AB) during pregnancy can result in considerable maternal and foetal adverse outcomes. Production of extended-spectrum beta-lactamase (ESBL) is a major antibiotic resistance mechanism by Enterobacteriaceae. OBJECTIVES:To determine the global preval...

journal_title：International journal of clinical practice

authors： Mansouri F,Sheibani H,Javedani Masroor M,Afsharian M

更新日期：2019-09-18 00:00:00

abstract：OBJECTIVE:To investigate the accuracy of three non-invasive blood pressure (BP) devices in atrial fibrillation (AF) compared with invasive arterial BP. METHODS:One hundred patients aged 45-90 years, 63% male (50 in AF and 50 age matched controls in sinus rhythm [SR]) were identified with arterial lines measuring beat-...

journal_title：International journal of clinical practice

authors： Eysenck W,Ammar A,Kanthasamy V,Freemantle N,Veasey RA,Patel NR,Furniss SS,Sulke N

更新日期：2019-08-29 00:00:00

abstract：AIMS:Few studies have evaluated the long-term impact of interventions on antibiotic prescription for lower respiratory tract infections (LRTI). This study was aimed at evaluating the use of antibiotics prescribed for LRTIs by general practitioners (GP) who underwent a multifaceted intervention carried out 6 years earli...

journal_title：International journal of clinical practice

authors： Molero JM,Moragas A,González López-Valcárcel B,Bjerrum L,Cots JM,Llor C

更新日期：2019-05-01 00:00:00

abstract：AIMS:To examine the relationship between costs of hyperglycaemia drug treatment and glycemic control amongst people with type 2 diabetes (T2D). METHODS:This observational study utilised data from the QUALIDIAB database on 3,452 T2D patients seen in Diabetes Centers in Argentina. Patients were classified according to t...

journal_title：International journal of clinical practice

authors： Elgart JF,Silvestrini C,Prestes M,Gonzalez L,Rucci E,Gagliardino JJ

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Peripheral arterial disease (PAD) is an underdiagnosed prevalent disease which implies high cardiovascular risk. Professionals usually depend on physical examination to screen for PAD. OBJECTIVE:To assess the diagnostic accuracy of physical examination to screen for PAD in a rural Primary Care population ...

journal_title：International journal of clinical practice

authors： Herráiz-Adillo Á,Piñar-Serrano O,Mariana-Herráiz JÁ,Martínez-Vizcaíno V,Pozuelo-Carrascosa DP,Notario-Pacheco B

更新日期：2018-11-01 00:00:00

abstract：AIMS:To describe trends and outcomes during admission for solid organ transplant in people with or without type 2 diabetes in Spain, 2001-2015. METHODS:We used national hospital discharge data to select all hospital admissions for kidney, lung, heart, and liver transplant. We estimated admission rates stratified by ty...

journal_title：International journal of clinical practice

authors： de Miguel-Yanes JM,Jiménez-García R,de Miguel-Díez J,Hernández-Barrera V,Méndez-Bailón M,Muñoz-Rivas N,López-de-Andrés A

更新日期：2018-10-13 00:00:00

abstract：AIM:Splenectomised patients are associated with lifelong risk of fatal overwhelming post-splenectomy infection (OPSI), which is mostly caused by Streptococcus pneumoniae. Today OPSI cases can still be reported even in patients with appropriate vaccination. In our study, the levels of vaccine-specific memory B- and T ce...

journal_title：International journal of clinical practice

authors： Gazi U,Karasartova D,Sahiner IT,Gureser AS,Tosun O,Derici MK,Dolapci M,Taylan Ozkan A

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Exhaustion is the perception of low energy. Little is known about how exhaustion persists, remits or reappears over time in patients with chronic obstructive pulmonary disease (COPD) or how to predict these events. We determined the likelihood of transitions between states of exhaustion and no ...

journal_title：International journal of clinical practice

authors： Medina-Mirapeix F,Bernabeu-Mora R,Giménez-Giménez LM,Montilla-Herrador J,García-Vidal JA,Benítez-Martínez J

更新日期：2018-05-01 00:00:00

abstract：AIMS:To evaluate in a real-world setting the effectiveness of exenatide once-weekly (ExQW) in patients with T2D and to determine predictors of glycaemic and weight response to this drug at 6 months. METHODS:Observational, retrospective, multicenter study in adult patients with T2D and BMI ≥30 kg/m2 from 4 tertiary Spa...

journal_title：International journal of clinical practice

authors： Gorgojo-Martínez JJ,Gargallo-Fernández MA,Brito-Sanfiel M,Lisbona-Catalán A

更新日期：2018-03-01 00:00:00

abstract：:Graham Jackson introduced the concept that erectile dysfunction was a marker for undiagnosed cardiovascular disease and future events. Unfortunately this had had modest impact on CVD management as ED is not incorporated into current risk calculators. In this paper, we examine recent evidence as to whether ED should be...

journal_title：International journal of clinical practice

authors： Hackett G,Kirby M

更新日期：2018-02-01 00:00:00

abstract：AIM:To determine the prevalence of computer vision syndrome (CVS) and ergonomic practices among students in the Faculty of Medical Sciences at The University of the West Indies (UWI), Jamaica. METHOD:A cross-sectional study was done with a self-administered questionnaire. RESULTS:Four hundred and nine students partic...

journal_title：International journal of clinical practice

authors： Mowatt L,Gordon C,Santosh ABR,Jones T

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Cardiovascular medications are effective in prevention of cardiovascular diseases (CVD); however, medication non-adherence contributes to morbidity and mortality. OBJECTIVE:This systematic review and meta-analysis aims to summarise the evidence regarding the relationship between characteristics of drug th...

journal_title：International journal of clinical practice

authors： Schneider APH,Gaedke MÂ,Garcez A,Barcellos NT,Paniz VMV

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Although the relationship of elevated serum uric acid levels and cardiovascular disease has been established in a great number of studies, the causal relevance of this finding remains ambiguous. An approach to evaluate the causal relevance of biomarkers is to exploit the natural randomised allocation of alle...

journal_title：International journal of clinical practice

authors： Kei A,Koutsouka F,Makri A,Elisaf M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Nineteen million adults worldwide are in need of palliative care. Of those who have access to it, 80% fail to receive an efficient management of symptoms. OBJECTIVES:To assess the effectiveness and safety of mindfulness meditation for palliative care patients. METHODS:We searched CENTRAL, MEDLINE, Embase, ...

journal_title：International journal of clinical practice

authors： Latorraca COC,Martimbianco ALC,Pachito DV,Pacheco RL,Riera R

更新日期：2017-12-01 00:00:00

abstract：AIMS:Patients with advanced type 2 diabetes (T2D) and high glycated haemoglobin (HbA1c) values can be difficult to treat because of their severe metabolic disease. This pooled analysis examined the treatment effects of exenatide twice daily (BID), exenatide once weekly (QW) and insulin in patients with high baseline Hb...

journal_title：International journal of clinical practice

authors： Busch RS,Ruggles J,Han J,Hardy E

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Inappropriate drug prescribing has increased especially in developing countries where systems for monitoring medicine use are not well developed. This increases the rate of antimicrobial resistance. The study aim was to assess the prescribing patterns among urban primary health facilities in Botswan...

journal_title：International journal of clinical practice

authors： Mashalla Y,Setlhare V,Massele A,Sepako E,Tiroyakgosi C,Kgatlwane J,Chuma M,Godman B

更新日期：2017-12-01 00:00:00

abstract：AIM:We analysed the effectiveness and safety of outpatient parenteral antibiotic therapy (OPAT) in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in patients admitted to home hospitalisation units (HHU). METHODS:Retrospective multicentre study of patients with AECOPD included in the Spanish OPAT ...

journal_title：International journal of clinical practice

authors： Ponce González MA,Mirón Rubio M,Mujal Martinez A,Estrada Cuxart O,Fiuza Perez D,Salas Reinoso L,Fernández Fabrellas E,Chiner Vives E

更新日期：2017-12-01 00:00:00

abstract：AIM:To raise awareness on nocturia disease burden and to provide simplified aetiologic evaluation and related treatment pathways. METHODS:A multidisciplinary group of nocturia experts developed practical advice and recommendations based on the best available evidence supplemented by their own experiences. RESULTS:Noc...

journal_title：International journal of clinical practice

authors： Oelke M,De Wachter S,Drake MJ,Giannantoni A,Kirby M,Orme S,Rees J,van Kerrebroeck P,Everaert K

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION AND OBJECTIVES:Persistence with antimuscarinic (AM) drugs prescribed for overactive bladder (OAB) is poor. This study aimed to compare persistence and adherence with the beta-3-adrenoceptor agonist mirabegron (MIR) vs AMs over 12 months. PATIENTS AND METHODS:This retrospective cohort analysis included pat...

journal_title：International journal of clinical practice

authors： Wagg AS,Foley S,Peters J,Nazir J,Kool-Houweling L,Scrine L

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Lozenges containing Amylmetacresol and 2,4-Dichlorobenzylalcohol (AMC/DCBA, eg Strepsils® ) are marketed as a remedy for acute sore throat. This over-the-counter formulation has antiseptic and local anaesthetic qualities. OBJECTIVES:The objective of this systematic review and meta-analysis is to evaluate th...

journal_title：International journal of clinical practice

authors： Weckmann G,Hauptmann-Voß A,Baumeister SE,Klötzer C,Chenot JF

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVES:This study evaluates the effectiveness, safety and costs of switching to a rilpivirine/emtricitabine/tenofovir disoproxil fumarate (RPV/FTC/TDF) regimen in treatment-experienced HIV-1-infected patients with sustained virological suppression. METHODS:Observational, prospective study. Study population include...

journal_title：International journal of clinical practice

authors： Arrabal-Durán P,Rodríguez-González CG,Chamorro-de-Vega E,Gijón-Vidaurreta P,Herranz-Alonso A,Sanjurjo-Sáez M

更新日期：2017-08-01 00:00:00

abstract：AIMS:To assess the safety and efficacy of omarigliptin in subjects with type 2 diabetes mellitus (T2DM) and chronic renal impairment (RI). METHODS:Patients with T2DM with moderate RI (estimated glomerular filtration rate [eGFR] ≥30 to <60 mL/min/1.73 m2 ) (N=114), severe RI (eGFR <30 mL/min/1.73 m2 ) (N=55) or end-sta...

journal_title：International journal of clinical practice

authors： Chacra A,Gantz I,Mendizabal G,Durlach L,O'Neill EA,Zimmer Z,Suryawanshi S,Engel SS,Lai E

更新日期：2017-06-01 00:00:00

abstract：AIMS:To establish the effectiveness of antidiabetic therapy and the frequency of clinical inertia in the management of type 2 diabetes mellitus in Colombia. METHODS:A cross-sectional study with follow-up of patients who had been treated for at least 1 year and were receiving medical consultation for antidiabetic treat...

journal_title：International journal of clinical practice

authors： Machado-Duque ME,Ramírez-Riveros AC,Machado-Alba JE

更新日期：2017-06-01 00:00:00

abstract：AIM:Real-world data on treatment patterns/outcomes in patients with advanced melanoma, while scarce, are useful for health technology assessments that govern patient access in many countries. We collected retrospective data on treatment patterns among patients in France, Germany and the UK with Stage IIIB/IIIC melanoma...

journal_title：International journal of clinical practice

authors： Harries M,Mohr P,Grange F,Ehness R,Benjamin L,Siakpere O,Barth J,Stapelkamp C,Pfersch S,McLeod L,Wolowacz S,Kaye JA,Kontoudis I

更新日期：2017-05-01 00:00:00

abstract：AIMS/OBJECTIVES:In the BESIDE study, combination therapy (antimuscarinic [solifenacin] and β3 -adrenoceptor agonist [mirabegron]) improved efficacy over solifenacin monotherapy without exacerbating anticholinergic side effects in overactive bladder (OAB) patients; however, a potential synergistic effect on the cardiova...

journal_title：International journal of clinical practice

authors： Drake MJ,MacDiarmid S,Chapple CR,Esen A,Athanasiou S,Cambronero Santos J,Mitcheson D,Herschorn S,Siddiqui E,Huang M,Stoelzel M

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Smoking has important health and economic consequences for individuals and society. This study expands the understanding of work-related burden associated with smoking and benefit of smoking cessation across the US, European Union (EU) and China using large-scale, representative survey methodology. METHODS:...

journal_title：International journal of clinical practice

authors： Baker CL,Flores NM,Zou KH,Bruno M,Harrison VJ

更新日期：2017-01-01 00:00:00

abstract：AIM:To assess attitudes and beliefs towards benign prostatic hyperplasia (BPH)/ lower urinary tract symptoms (LUTS) and its treatment among patients and physicians in Latin America, Asia Pacific and the Commonwealth of Independent States (CIS). METHODS:Cross-sectional, quantitative study conducted between December 201...

journal_title：International journal of clinical practice

authors： Ertel P,Adalig B,Demircan I,Lartey B,Manyak MJ

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to explore the feasibility of using low dose radiation and low concentration contrast media in enhanced CT examinations in children with congenital heart disease. MATERIALS AND METHODS:Ninety patients with congenital heart disease were randomly divided into three groups of 30 patien...

journal_title：International journal of clinical practice

authors： Liu Z,Song L,Yu T,Gao J,Zhang Q,Jiang L,Liu Y,Peng Y

更新日期：2016-09-01 00:00:00